Unlike many probiotics, DS-01® makes it to the gut alive.
Seed's ViaCap® technology is engineered for targeted delivery along the GI tract.
Learn More
Learn More
Survivability
Many probiotics—like gummies, powders, and drinks—dissolve during digestion. DS-01®’s proprietary ViaCap® system is engineered to protect probiotic strains from stomach acid, digestive enzymes, and bile.
ViaCap® Technology
Our proprietary dual-capsule system is built for a timed release to the colon: the prebiotic outer capsule releases in the upper GI tract and the probiotic inner capsule continues to the large intestine.
- Outer capsule made from cellulose protects probiotics and prebiotics as they travel through the GI tract.
- Plant-based formula—no synthetic coatings like similar cap-in-cap systems.
- Engineered for precision delivery to the colon, where bacteria is needed to work effectively.
Digestive Survivability Testing (SHIME®)
To evaluate the survival of our probiotics, we use a Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)—the closest simulation of the human gastrointestinal system. It recreates the physiological conditions of digestion (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids) and time spent in each step to represent the dynamic microbial conditions of the human gastrointestinal tract.
The DS-01® difference:Benefits that build over time
Results you can feel in as little as 7 days.*
See Clinical Evidence
See Clinical Evidence
Clinical Trials
The majority of dietary supplements have never been tested in human clinical trials on the actual product.
DS-01® has been tested in multiple full formulation randomized, placebo-controlled clinical trials, including the largest probiotic clinical trial evaluating bloating, in otherwise healthy women and men.
In addition, DS-01®’s ingredients have been validated in clinical trials to assess benefits in and beyond the gut.
The Impact of Clinical Proof
Randomized, placebo-controlled trials provide clarity and bring rigor to scientific research for various reasons, including:
- Eliminate bias
- Rule out placebo-effect
- Establish causality
- Validate efficacy
By testing DS-01® as a full formulation, the entire product is validated for tolerability and efficacy.
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In Seed’s largest clinical trial on DS-01, 350 men and women were evaluated using clinically-validated GI endpoints in partnership with leading gastroenterology physicians and academic microbiome researchers. This study shows real-world relevance with participants from 40 states and territories, reflecting the broader US population.
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Bloating + Gas Relief*
- DS-01 resulted in a significant reduction in bloating and gas symptoms compared to placebo.
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Improvement in Regularity*
- DS-01 improved bowel habits, specifically addressing occasional constipation-related discomfort, stool quality, and supporting regularity compared to placebo.
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Reduced GI Discomfort*
- DS-01 led to a reduction in abdominal discomfort compared to placebo.
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Improved Quality of Life *
- DS-01 improved GI-related quality of life compared to placebo. This included greater food enjoyment, reduced food avoidance, and significantly less disruption of physical activity due to digestive events
How to Use:
Take 2 capsules daily, with or without food, day or night.
24 strain formula for transformative gut benefits*
View Strains + Ingredients
View Strains + Ingredients
Strains + Ingredients
DS-01® is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.
Probiotic Inner Capsule
Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and tested for all 14 classes of allergens identified by the European Food Safety Authority (EFSA).
Prebiotic Outer Capsule
Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.
Other Ingredients
- Vegan Outer [Hypromellose, Sodium Copper Chlorophyllin Color] and Inner [Hypromellose, Water] Capsules
- Organic Rice Fiber
- Organic Rice Extract
Digestive Health Probiotic Blend ® -----224 MG / 38.7 BILLION AFU
Digestive Health Probiotic Blend ® -----224 MG / 38.7 BILLION AFU
Probiotic blend for digestive health, gut barrier integrity, and healthy immune response.
SUPPORTING STRAINS:
Bifidobacterium breve SD-BR3-IT
Bifidobacterium longum SD-BB536-JP
Lacticaseibacillus rhamnosus HRVD113-US
Lactiplantibacillus plantarum SD-LP1-IT
Lacticaseibacillus rhamnosus SD-LR6-IT
Bifidobacterium lactis HRVD524-US
Bifidobacterium infantis SD-M63-JP
Bifidobacterium lactis SD-BS5-IT
Lacticaseibacillus casei HRVD300-US
Bifidobacterium breve HRVD521-US
Bifidobacterium lactis SD-150-BE
Bifidobacterium longum HRVD90b-US
Lacticaseibacillus rhamnosus SD-GG-BE
Limosilactobacillus reuteri RD830-FR
Lactobacillus crispatus SD-LCR01-IT
Limosilactobacillus fermentum SD-LF8-IT
Cardiovascular Health Probiotic Blend® -----36 MG / 3.34 BILLION AFU
Cardiovascular Health Probiotic Blend® -----36 MG / 3.34 BILLION AFU
Ligilactobacillus salivarius SD-LS1-IT
Bifidobacterium longum SD-CECT7347-SP
Lacticaseibacillus casei SD-CECT9104-SP
Bifidobacterium lactis SD-CECT8145-SP
Cardiovascular Health Probiotic Blend® -----13 MG 4.21 BILLION AFU
Cardiovascular Health Probiotic Blend® -----13 MG 4.21 BILLION AFU
Lactiplantibacillus plantarum SD-LPLDL-UKBifidobacterium lactis SD-MB2409-IT
Micronutrient Synthesis Probiotic Blend® -----36 MG7.32 BILLION AFU
Micronutrient Synthesis Probiotic Blend® -----36 MG7.32 BILLION AFU
Bifidobacterium lactis SD-BA5IT Limosilactobacillus reuteri SD-LRE2-IT
Questions?We're here to help.
When will I feel something?
When will I feel something?
It is normal to feel effects in the digestive tract in as little as 24-48 hours. Other longer term benefits like cardiovascular health and gut immune function may take longer. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.
How do I take DS-01® Daily Synbiotic?
How do I take DS-01® Daily Synbiotic?
Adults—take 2 capsules daily, all at once. You can take DS-01 with or without food and maintain the efficacy of the product. However, you know your body best—find the best time of day to take for you.
Why should I take DS-01® Daily Synbiotic?
Why should I take DS-01® Daily Synbiotic?
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is the microbiome. By supplementing your gut microbial makeup, DS-01® provides benefits for both digestive and whole body health.
Do I need to refrigerate my DS-01® Daily Synbiotic
Do I need to refrigerate my DS-01® Daily Synbiotic
No refrigeration necessary.
Do I have to sign up for a subscription?
Do I have to sign up for a subscription?
Yes. We believe that probiotics and prebiotics, alongside diet, nutrition, exercise, and lifestyle, are cornerstone tools to building foundational health. Clinical research shows that continuous, daily intake is the best way to get the most out of your synbiotic. By signing up for a subscription, you’ll easily be able to build DS-01® into your routine.
But we want you to feel good about what you’re taking. That’s why we want you to try DS-01®, risk-free for 30 days. You may also reschedule or cancel your subscription easily from your account at any time.
What does my subscription to DS-01® Daily Synbiotic include?
What does my subscription to DS-01® Daily Synbiotic include?
Your monthly subscription includes a 30-day supply of DS-01®. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a complimentary travel vial that holds a week’s worth of your DS-01®, so you never miss a day on the go.
Is DS-01® Daily Synbiotic compatible with my diet or dietary restrictions?
Is DS-01® Daily Synbiotic compatible with my diet or dietary restrictions?
DS-01® is tested for: Dairy, Gluten, Soy, GMOs, Nuts, Shellfish, Sesame, Glyphosate/AMPA, and 14 classes of allergens defined by European Food and Safety Authority (EFSA)
It adheres to the following diets: Vegan • Vegetarian • Ketogenic • Gluten-Free • Intermittent Fasting
What is your 30 day risk-free guarantee? Do you accept returns?
What is your 30 day risk-free guarantee? Do you accept returns?
If for any reason you are not satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product less shipping, VAT, and duties—no questions asked. Refunds apply to your first order only, not any subsequent shipments. For all subsequent shipments, you may reschedule or cancel at any time in your account.
Note that Sustainable Refill Program orders are considered final sale 30 days after delivery.
Is DS-01® Daily Synbiotic safe to take while I'm pregnant or breastfeeding?
Is DS-01® Daily Synbiotic safe to take while I'm pregnant or breastfeeding?
As with any dietary supplement or new health protocol contemplated during pregnancy or lactation, we recommend speaking with your physician or obstetrician before you start consuming DS-01® Daily Synbiotic.
Do you ship internationally?
Do you ship internationally?
Yes—we ship to many countries internationally.
















